The gains are developing so fast and furiously, it is becoming hard to keep up. Isn’t that wonderful? Need some examples?
Researchers at CHOP (Children’s hospital of Phila) discovered that hi grade glioma brain tumors have tiny pieces of mRNA missing which make it hard to treat these cancers with immune therapy. They are developing a plan targeting the cells with new immune therapeutics and expect to role this out to adult GBM and neuroendocrine tumors (August 15, CHOP)
Even with chemo, AML (Acute myelogenous leukemia is notorious for re- appearing (Blood Cancer Discovery) A way to potentially disarm the chemo resistance by flipping a genetic switch is in the works.
“Nature Medicine” published that for high risk pancreatic and colorectal cancers, that recur after therapy, a vaccine targeting genetic mutation was effective in 90% pancreatic and 50% colo-rectal cases. They added a delivery system carrying the vaccine right to the lymph nodes where immune cells are held.
Too complicated? How about tapping into something that YOU can work on? Evidence shows that 30 minutes of exercise (especially for our lovely breast cancer survivors) can stimulate anti cancer myokine protein production during and after treatment. So “just do it” becomes a cure enhancement.
Columbia Engineering built a cancer therapy that makes bacteria and viruses work as a team. Stay with me. Bacteria have affinity for tumor cells. They tapped that power and hid cancer killing viruses into the bacteria to sneak past the the immune system (Native Biomedical Engineering). Get outta here!
Virginia Tech is working with MUSC to develop a way to target the dormant GBM cells that recur, wake up after therapy and rebuild tumor. JM2 a small peptide was found in mice to attack the GBM stem cells while unharming normal brain cells, offering hope for attacking the root cause of recurrence.
Most common in men…Already for prime time , hyfu and focal treatments for localized prostate cancer, as well as pluvicto radioligand for metastatic prostate. How about most common in women, breast cancer research have scientists now looking at western honey bee venom therapy. Come on.
If it wasn’t so fantastic, it would be exhausting. This is information just in August 2025. Can you imagine what is to come? Yay for science, hooray for patients and yes, I am a geek.